Without enquiry or reply, it's squarer to be more certain (5)
I believe the answer is:
surer
'more certain' is the definition.
('sure' can be a synonym of 'certain')
I cannot understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for surer that I've seen before include "faster" , "More certain and positive" , "more right?" .)