Without exception, small child needs a friend (7)
I believe the answer is:
totally
'without exception' is the definition.
(I've seen this in another clue)
'small child needs a friend' is the wordplay.
'small child' becomes 'tot' (tot can mean a baby or toddler).
'needs' is a charade indicator (letters next to each other).
'a friend' becomes 'ally' (an ally is a friend or supporter).
'tot'+'ally'='TOTALLY'
(Other definitions for totally that I've seen before include "without reserve" , "Absolutely" , "Completely, entirely" , "To the full extent" , "in every respect" .)