Without, with "of" (6)
I believe the answer is:
devoid
'without with of' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for devoid that I've seen before include "Empty - do dive (anag)" , "Completely lacking" , "Entirely free (of)" , "Free (of something)" , "Entirely lacking" .)