Woman set about man from the outset, that's just it! (3,4,3)
I believe the answer is:
the fair sex
'woman set about man' is the definition.
I don't know anything about this answer so I can't judge whether this works.
'from the outset that's just it' is the wordplay.
I cannot really see how this works, but
'from' could be 'ex' and 'ex' is present in the answer.
'just' could be 'fair' ('fair' is associated in meaning with 'just') and 'fair' is found within the answer.
'it' could be 't' (abbreviation. e.g. in 'tis) and 't' is present in the answer.
The remaining letters 'hes' is a valid word which might be clued in a way I don't understand.
This may be the basis of clue (or it may be nonsense).
Can you help me to learn more?
(Another definition for the fair sex that I've seen is " Women?".)