Woman with pressure, upset (8)
I believe the answer is:
distress
'upset' is the definition.
(distressing is a kind of upseting)
'woman with pressure' is the wordplay.
'woman' becomes 'Di' (short for Diana).
'with' means one lot of letters go next to another.
'pressure' becomes 'stress' (I've seen this before).
'di'+'stress'='DISTRESS'
(Other definitions for distress that I've seen before include "Such a signal indicates trouble" , "Extreme anxiety or sorrow" , "Upset" , "Psychological suffering" , "Extreme sorrow or pain" .)