Woman with strain and grief (8)
I believe the answer is:
distress
'grief' is the definition.
(I've seen this before)
'woman with strain' is the wordplay.
'woman' becomes 'Di' (short for Diana).
'with' means one lot of letters go next to another.
'strain' becomes 'stress' (stress is a kind of strain).
'di'+'stress'='DISTRESS'
'and' acts as a link.
(Other definitions for distress that I've seen before include "Severe pain" , "Sadden" , "Anguish - trouble - danger" , "Pain, trouble or sorrow" , "Suffering, worry" .)