Woman's nomination produces regret (14)
I believe the answer is:
disappointment
'regret' is the definition.
(thesaurus)
'woman's nomination' is the wordplay.
I cannot really understand how this works, but
'woman's' could be 'dis' (Di is short for Diana) and 'dis' is found within the answer.
The remaining letters 'appointment' is a valid word which might be clued in a way I don't understand.
This explanation may well be incorrect...
'produces' is the link.
Can you help me to learn more?
(Other definitions for disappointment that I've seen before include "Setback" , "unhappiness" , "Frustrating thing" , "Frustration" , "Let-down" .)