Women facing trouble sob (4)
I believe the answer is:
wail
'sob' is the definition.
(thesaurus)
'women facing trouble' is the wordplay.
'women' becomes 'w'.
'facing' says to put letters next to each other.
'trouble' becomes 'ail' ('ail' can be a synonym of 'trouble'**).
'w'+'ail'='WAIL'
(Other definitions for wail that I've seen before include "Lament loudly" , "Mournful cry" , "(Make a) plaintive cry" , "Lamentation" , "blub" .)