Word with friendly or interface (4)
I believe the answer is:
user
This clue is a double definition.
'word with friendly' is the first definition.
(I've seen this in another clue)
'interface' is the second definition.
(user interface is a kind of interface)
(Other definitions for user that I've seen before include "With 1a [NEW] he'll need different login" , "Manipulator" , "Manipulative woman" , "Drug taker" , "Ruse for employer" .)