Work of art that's drawn by English lake (6)
I believe the answer is:
pastel
'work of art that's drawn' is the definition.
I can't judge whether this definition defines the answer.
'by english lake' is the wordplay.
'by' becomes 'past' (synonyms).
'english' becomes 'E' (abbreviation as in OED).
'lake' becomes 'L' (geographical abbreviation).
'past'+'e'+'l'='PASTEL'
Can you help me to learn more?
(Other definitions for pastel that I've seen before include "pigments mixed with gum" , "Staple (anag)" , "Staple light colour" , "Crayon used in art" , "Delicate and pale in colour" .)