Work with dog belonging to us (6)
I believe the answer is:
labour
'work' is the definition.
(I know that work can be written as labour)
'with dog belonging to us' is the wordplay.
'with' is a charade indicator (letters next to each other).
'dog' becomes 'lab' (short for labrador).
'belonging to us' becomes 'our' (us, you and me).
'lab' next to 'our' is 'LABOUR'.
(Other definitions for labour that I've seen before include "opposition" , "Hard work, toil" , "End of term" , "Donkey-work" , "Men are never in this" .)