Work with one's hands (5)
I believe the answer is:
knead
'work with one's hands' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for knead that I've seen before include "Massage with hands" , "Work dough or massage flesh" , "Work with finger movements" , "Massage - naked (anag)" , "Somehow work in" .)