Crossword Genius

Working in advance reversed failure (4)

Ross

I believe the answer is:

nono

(Other definitions for nono that I've seen before include "Impossibility" , "Non-starter (colloq.)" , "Something that would be totally unacceptable" , "Something not acceptaable" , "Something totally unacceptable (informal)" .)

I've seen this clue in The Times.
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