Working practice of French secretary upset primates (6)
I believe the answer is:
apedom
'primates' is the definition.
(apedom means all apes)
'working practice of french secretary upset' is the wordplay.
'working practice' becomes 'MO' (modus operandi).
'of french' becomes 'de' ('of' in French).
'secretary' becomes 'PA' (abbreviation for personal assistant).
'upset' is a reversal indicator.
'mo'+'de'+'pa'='modepa'
'modepa' written backwards gives 'APEDOM'.
(Other definitions for apedom that I've seen before include "Where primates are found" , "class of swingers?" , "condition of primates" .)