Wrath in the midst of dangers (5)
I believe the answer is:
anger
'wrath' is the definition.
(synonyms)
'midst of dangers' is the wordplay.
'midst of' says to take the centre.
The middle of 'dangers' is 'ANGER'.
'in the' acts as a link.
(Other definitions for anger that I've seen before include "Strong displeasure" , "Wrath; annoy" , "Feeling of vexation" , "Spleen" , "Great annoyance" .)