Wry twist (5)
I believe the answer is:
irony
'wry twist' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for irony that I've seen before include "Satirical speech form" , "Sarcastic humour" , "The use of words which is the opposite of what they say" , "Satire, sarcasm" , "Socrates used it" .)