Yank in London’s Burning (4)
I believe the answer is:
itch
'burning' is the definition.
(both can mean a strong desire)
I don't understand how the rest of the clue works.
(Other definitions for itch that I've seen before include "Contagious skin infection" , "Prickling" , "Hunger, longing" , "following seven years in union?" , "Nagging wish" .)