Yearning to hold one work of art (8)
I believe the answer is:
painting
'work of art' is the definition.
(I've seen this before)
'yearning to hold one' is the wordplay.
'yearning' becomes 'panting' (to pant for something is to yearn for it).
'to hold' indicates putting letters inside.
'one' becomes 'I' (Roman numeral).
'panting' going around 'i' is 'PAINTING'.
(Other definitions for painting that I've seen before include "Work of art" , "Constable possibly" , "Work of a kind" , "picture" , "Graphic art" .)