Young girl needs help surrounded by males (6)
I believe the answer is:
maiden
'young girl' is the definition.
(I've seen this before)
'help surrounded by males' is the wordplay.
'help' becomes 'aid' (synonyms).
'surrounded by' is an insertion indicator.
'males' becomes 'men' (man is a kind of male).
'aid' going inside 'men' is 'MAIDEN'.
'needs' is the link.
(Other definitions for maiden that I've seen before include "First ever public address" , "Over in cricket in which no runs are scored" , "over, you won't score" , "Of an aunt, unmarried" , "Six dot balls" .)