Young man inspired by Madonna's craft (7)
I believe the answer is:
masonry
'craft' is the definition.
(craft of a stonemason)
'young man inspired by madonna's' is the wordplay.
'young man' becomes 'son' (male child).
'inspired by' is an insertion indicator (some letters breathed in or 'inspired' by others).
'madonna' becomes 'Mary' (synonyms).
'son' going into 'mary' is 'MASONRY'.
(Other definitions for masonry that I've seen before include "brickwork" , "Skill in construction" , "Building work in stone" , "Stonework" .)