Your setter, so vigorous getting up for an old fellow (10)
I believe the answer is:
methuselah
'an old fellow' is the definition.
(most long-lived figure in the Bible)
'your setter so vigorous getting up' is the wordplay.
'your setter' becomes 'me' (the crossword setter of this puzzle).
'so' becomes 'thus' (synonyms).
'vigorous' becomes 'hale' (both can mean healthy).
'getting up' shows that the letters should be reversed in order.
'hale' reversed gives 'elah'.
'me'+'thus'+'elah'='METHUSELAH'
'for' is the link.
(Other definitions for methuselah that I've seen before include "so much champagne" , "Large wine bottle -- biblical patriarch" , "I'm an old man" , "One very old" , "Old man of the Bible" .)