A friend in Lyon on leave with a friend in Barcelona (5)
I believe the answer is:
amigo
'a friend' is the definition.
('friend' in Spanish)
'lyon on leave with a friend in barcelona' is the wordplay.
I cannot really understand how this works, but
'leave' could be 'go' and 'go' is located in the answer.
'a friend' could be 'ami' (I've seen this before) and 'ami' is found in the answer.
No letters remain.
This may be the basis of clue (or it may be nonsense).
'in' is the link.
Can you help me to learn more?
(Other definitions for amigo that I've seen before include "Spanish word meaning friend" , "Hispanic comrade" , "in a foreign land, my friend?" , "Pal from Madrid?" , "friend from Barcelona" .)