Awry, like part of London (5)
I believe the answer is:
askew
'awry' is the definition.
(I know that awry can be written as askew)
'like part of london' is the wordplay.
'like' becomes 'as'.
'part of london' becomes 'kew' (I've seen this before).
'as'+'kew'='ASKEW'
(Other definitions for askew that I've seen before include "Wonky" , "Leaning to one side" , "Off-centre" , "Crookedly" , "Obliquely" .)