Calling race (6)
I believe the answer is:
career
I believe this is a double definition.
'calling' is the first definition.
(synonyms)
'race' is the second definition.
(career can mean to run or move out of control)
(Other definitions for career that I've seen before include "Employment history" , "go very fast" , "Not intellectual" , "someone in profession" , "Rush wildly" .)