Change with regard to group of students (6)
I believe the answer is:
reform
'change' is the definition.
(I know that reform is a type of change)
'with regard to group of students' is the wordplay.
'with regard' becomes 're' ('re' means regarding or about).
'to group of students' becomes 'form'.
're'+'form'='REFORM'
(Other definitions for reform that I've seen before include "Show improvement" , "Go straight" , "Change one's ways (for the better?)" , "Mend one's ways" , "Abandon evil practices" .)