Dog biting large colonist (7)
I believe the answer is:
settler
'colonist' is the definition.
(I know that colonist can be written as settler)
'dog biting large' is the wordplay.
I cannot quite see how this works, but
'large' could be 'l' (eg in clothes sizes) and 'l' is found within the answer.
'dog' could be 'setter' (setter is a type of dog) and 'setter' is found within the remaining letters.
This accounts for all the letters.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for settler that I've seen before include "One taking up residence in a new area" , "newcomer, perhaps" , "One colonising new area" , "Early colonist" , "Colonist, pioneer" .)