Get the better of inappropriate comedian (6)
I believe the answer is:
outwit
'get the better of' is the definition.
(both can mean to outsmart)
'inappropriate comedian' is the wordplay.
'inappropriate' becomes 'out'.
'comedian' becomes 'wit' (a witty person).
'out'+'wit'='OUTWIT'
(Other definitions for outwit that I've seen before include "Dupe" , "Be too smart for, defeat" , "Get the better of by being smarter" , "Hoodwink" , "Deceive through greater ingenuity" .)