Harmful recreational drug is ordered (4)
I believe the answer is:
bade
'is ordered' is the definition.
(past tense of 'bid' as in to order)
'harmful recreational drug' is the wordplay.
'harmful' becomes 'bad' (similar in meaning).
'recreational drug' becomes 'e' (E can refer to ecstasy).
'bad'+'e'='BADE'
(Other definitions for bade that I've seen before include "Ordered" , "Invited" , "Commanded with bead" .)