Himalayas setting (4)
I believe the answer is:
asia
'himalayas setting' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for asia that I've seen before include "One-third of all land" , "The nations of the East, collectively" , "A vast number of people have lived here" , "Earth's largest continent" , "Large continent" .)