Joined university and connected with no one (6)
I believe the answer is:
united
'joined' is the definition.
(synonyms)
'university and connected with no one' is the wordplay.
'university' becomes 'uni' (short for university).
'and' is a charade indicator (letters next to each other).
'connected' becomes 'tied' ('tie' can be a synonym of 'connect').
'with no' indicates named letters should be taken away.
'one' becomes 'i' (Roman numeral).
'tied' with 'i' removed is 'ted'.
'uni'+'ted'='UNITED'
(Other definitions for united that I've seen before include "Unified" , "Affiliated" , "Joined or combined" , "Of one mind" , "joined with others" .)