Crossword Genius

Lead-in to course (3)

Ross

I believe the answer is:

dis

(Other definitions for dis that I've seen before include "Prefix denoting the opposite of the base word" , "Speak disrespectfully to (colloq.)" , "The god Pluto" , "Greek underworld" , "Show contempt" .)

I've seen this clue in The New York Times.
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