Live as Liberal in college, always a sceptic (10)
I believe the answer is:
unbeliever
'a sceptic' is the definition.
(a sceptic doesn't believe in something)
'live as liberal in college always' is the wordplay.
'live as' becomes 'be' (to be something can mean to live as it).
'liberal' becomes 'l' (abbreviation).
'in' is an insertion indicator.
'college' becomes 'uni' (short for university).
'always' becomes 'ever' (synonyms).
'be'+'l'='bel'
'bel' put within 'uni' is 'unbeli'.
'unbeli'+'ever'='UNBELIEVER'
(Another definition for unbeliever that I've seen is " atheist".)