Crossword Genius

Loner we led astray to become a worthless person (4-2-4)

Ross

I believe the answer is:

neer-do-well

'a worthless person' is the definition.
(I've seen this before)

'loner we led astray' is the wordplay.
'astray' indicates anagramming the letters.
'loner'+'we'+'led'='lonerweled'
'lonerweled' anagrammed gives 'NEER-DO-WELL'.

'to become' acts as a link.

(Other definitions for neer-do-well that I've seen before include "Good-for-nothing" , "Useless person" , "Useless type" , "Wastrel" , "Lazy irresponsible person" .)

I've seen this clue in The Telegraph.
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