Nice changes in benefit getting skilled (10)
I believe the answer is:
proficient
'skilled' is the definition.
(similar in meaning)
'nice changes in benefit' is the wordplay.
'changes' indicates an anagram.
'in' means one lot of letters goes inside another.
'benefit' becomes 'profit' (synonyms).
'nice' anagrammed gives 'cien'.
'cien' placed within 'profit' is 'PROFICIENT'.
'getting' is the link.
(Other definitions for proficient that I've seen before include "Competent, thoroughly qualified" , "Well-skilled" , "Showing skill" , "having great facility" , "Able" .)