Crossword Genius

Pain (4)

Ross

(Other definitions for tire that I've seen before include "Wear out" , "Become weary" , "Flag" , "Become fatigued" , "Grow weary of rithe" .)

I've seen this clue in the LA Times, The Star Tribune, the Penny Press, The Guardian, The New York Times, The Mirror, The Telegraph and the Evening Standard.
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