Prayer for old prison head departing (6)
I believe the answer is:
orison
'prayer' is the definition.
(I know that prayer can be written as orison)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for orison that I've seen before include "O, no, sir, it makes a prayer" , "An archaic or literary prayer" , "Prayer - O no sir! (anag)" , "Supplication" .)