Region of ancient Mesopotamia (5)

I believe the answer is:

sumer

'region of ancient mesopotamia' is the definition.
(I've seen this in another clue)

This is all the clue.

(Other definitions for sumer that I've seen before include "old region of Mesopotamia" , "old civilisation" , "site of ancient civilization" , "Ancient region" .)

I've seen this clue in the LA Times and the Wall Street Journal.

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