An answer you can depend on being soft-hearted (5)
I believe the answer is:
reply
'an answer' is the definition.
('reply' can be a synonym of 'answer')
'can depend on being soft-hearted?' is the wordplay.
I cannot quite see how this works, but
'on' could be 're' (regarding) and 're' is found in the answer.
'soft' could be 'p' (musical abbreviation for 'piano') and 'p' is located in the answer.
This may be the basis of the clue (or it may be nonsense).
'you' acts as a link.
Can you help me to learn more?
(Other definitions for reply that I've seen before include "response is demanded" , "acknowledgement" , "Counter" , "Comeback" , "Come back" .)