Answer in holy book can start to ease isolation (10)
I believe the answer is:
quarantine
'isolation' is the definition.
(quarantine is a kind of isolation)
'answer in holy book can start to ease' is the wordplay.
I cannot really see how this works, but
'answer' could be 'a' (abbreviation eg in Q and A) and 'a' is present in the answer.
'in' is present in the answer.
'book' could be 'nt' (New Testament) and 'nt' is found within the answer.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for quarantine that I've seen before include "Place in isolation" , "solitary confinement" , "separate from others" , "Period of isolation to prevent spread of disease" , "Compulsory isolation to prevent spread of disease" .)