Material desire follows lust in the end (5)
I believe the answer is:
twill
'material' is the definition.
(twill is a kind of material)
'desire follows lust in the end' is the wordplay.
'desire' becomes 'will' (I've seen this in another clue).
'follows' means one lot of letters go next to another.
'in the end' says to take the final letters.
The last letter of 'lust' is 't'.
'will' after 't' is 'TWILL'.
(Other definitions for twill that I've seen before include "Fabric with distinctive weave" , "Ribbed cloth" , "Fabric woven to produce a surface of diagonal parallel ridges" , "Cloth with diagonal ribs" , "Material" .)