Run - and come to grief (4)

I believe the answer is:

trip

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'run' is the definition.
(thesaurus)

I don't understand the remainder of the clue.

(Other definitions for trip that I've seen before include "Excursion (while on drugs?)" , "Journey - cause to stumble" , "Catch one's foot" , "Run with light steps" , "Hallucinogenic drug experience - lose one's balance" .)

I've seen this clue in the Evening Standard.

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