A male nurse beside one's bottom put up fluid (5)
I believe the answer is:
enema
'fluid' is the definition.
Although both the answer and definition are singular nouns, I don't understand how one could define the other.
'a male nurse beside one's bottom put up' is the wordplay.
'male' becomes 'm' (common abbreviation).
'nurse' becomes 'en' (abbreviation for state-enrolled nurse).
'beside' is a charade indicator (letters next to each other) (I've seen this in other clues).
'bottom' indicates one should take the final letters.
'put up' is a reversal indicator.
The last letter of 'one' is 'e'.
'a'+'m'+'en'+'e'='amene'
'amene' back-to-front is 'ENEMA'.
Can you help me to learn more?
(Other definitions for enema that I've seen before include "In the end medical procedure" , "Suppository" , "Medical liquid introduced anally" , "Colonic irrigation" , "Bowel evacuator" .)