A means of making cloth set up to make money (5)
I believe the answer is:
moola
'money' is the definition.
(informal term for money)
'a means of making cloth set up' is the wordplay.
'means of making cloth' becomes 'loom' (machine for making cloth).
'set up' says the letters should be written backwards (in a down clue, letters go up).
'a'+'loom'='aloom'
'aloom' backwards is 'MOOLA'.
'to make' is the link.
(Other definitions for moola that I've seen before include "Dosh, dough" , "Money (slang)" , "11 [lolly]" , "Ackers, lolly" .)