A measure in operation (5)
I believe the answer is:
afoot
'in operation' is the definition.
('afoot' can mean taking place or in process)
'a measure' is the wordplay.
'measure' becomes 'foot' (foot is a kind of measure).
'a'+'foot'='AFOOT'
(Other definitions for afoot that I've seen before include "About to happen" , "in preparation" , "Astir" , "Brewing" , "Stirring" .)