A profit, not for the first time (5)

I believe the answer is:

again

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'not for the first time' is the definition.
(I've seen this in another clue)

I don't understand how the rest of the clue works.

Can you help me to learn more?

(Other definitions for again that I've seen before include "Furthermore" , "Moreover - a second time" , "Here we go ___" , "Ocne more" , "Next time" .)

I've seen this clue in The Times and The Telegraph.

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