Abandoned 500 felt irritation (7)
I believe the answer is:
ditched
'abandoned' is the definition.
(ditching is a kind of abandoning)
'500 felt irritation' is the wordplay.
I cannot quite understand how this works, but
'500' could be 'd' (Roman numeral for 500) and 'd' is located in the answer.
'irritation' could be 'itch' (an itch irritates you) and 'itch' is found in the answer.
The remaining letters 'ed' is a valid word which might be clued in a way I don't understand.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for ditched that I've seen before include "Got rid of" , "Dumped" , "Of plane, made forced landing on sea" , "Left in the lurch or landed plane in sea" .)