Abandons all hope in a spider's web (8)

I believe the answer is:

despairs

I'm a little stuck... Click here to teach me more about this clue!

'abandons all hope' is the definition.
(I've seen this in another clue)

'a spider's web' is the wordplay.
'a spider's' can be anagrammed to 'DESPAIRS'.
But, I am not clear how the anagram is indicated.

'in' acts as a link.

Can you help me to learn more?

(Other definitions for despairs that I've seen before include "Abandons hope" , "Loses all hope" .)

I've seen this clue in The Guardian.

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