About little lost fish (6)
I believe the answer is:
roughy
'about little lost fish' is the definition.
'roughy' can be an answer for 'fish' (roughy is a type of fish). I am not sure about the 'about little lost' bit.
'fish' is the wordplay.
I cannot really understand how this works, but
'fish' could be 'rough' (rough fish is a kind of fish) and 'rough' is found within the answer.
A single letter 'y' remains which might be clued in a way I don't see.
This explanation may well be incorrect...
(Other definitions for roughy that I've seen before include "[SOMETHING FISHY]" , "Marine fish" .)