Accompanied by comedian and husband (4)
I believe the answer is:
with
'accompanied by' is the definition.
(I've seen this before)
'comedian and husband' is the wordplay.
'comedian' becomes 'wit' (I've seen this before).
'and' says to put letters next to each other.
'husband' becomes 'h'.
'wit'+'h'='WITH'
(Other definitions for with that I've seen before include "Accompanied by" , "Possessing" , "Among" , "See 5" , "In the presence of" .)