Adjustment of liaison to separation (9)
I believe the answer is:
isolation
'separation' is the definition.
(I know that isolation is a type of separation)
'adjustment of liaison to' is the wordplay.
'adjustment of' is an anagram indicator (I've seen this in other clues).
'liaison'+'to'='liaisonto'
'liaisonto' is an anagram of 'ISOLATION'.
(Other definitions for isolation that I've seen before include "keeping apart" , "Quarantine; solitude" , "loneliness" , "Man could display this" , "Separation, solitariness" .)